FDPS anticorps

N° du produit ABIN5699809

Cet anticorps Lapin Polyclonal détecte spécifiquement FDPS dans WB, ELISA et IP. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour FDPS anticorps (ABIN5699809)

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDPS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-FDPS anticorps

Fonction: FDPS antibody

Immunogène: farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur FDPS

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Autre désignation: FDPS

Sujet:

Synonyms: Farnesyl pyrophosphate synthase (FPP synthase, FPS)|(2E,6E)-farnesyl diphosphate synthase|Dimethylallyltranstransferase|Farnesyl diphosphate synthase|Geranyltranstransferase|FDPS|FPS|KIAA1293

Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 39-41 kDa

ID gène: 2224

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation